Myrto Ischyropoulou / Max-Planck-Institut für Multidisziplinäre Naturwissenschaften
Nanoparticles for optimized cancer therapy

Pancreatic cancer is one of the deadliest types of cancers in humans. It is the fourth leading cause of cancer-related deaths in the western world. The early stages of the disease often progress without symptoms, so diagnosis is usually very late. Another problem: Advanced tumors – and their metastases – can no longer be completely removed. Chemotherapies, in turn, attack not only the tumor cells but also healthy cells throughout the body. Innovative nanoparticles could be a new approach to treat cancer more precisely. The approach was developed by a research team from the Max Planck Institute (MPI) for Multidisciplinary Sciences, the University Medical Center Göttingen (UMG), and the Karlsruhe Institute of Technology (KIT). The therapy is now to be optimized for clinical application as quickly as possible.

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Nano Ringe
Nanorings: New Building Blocks for Chemistry

Sandwich compounds are special chemical compounds used as basic building blocks in organometallic chemistry. So far, their structure has always been linear. Recently, researchers of Karlsruhe Institute of Technology (KIT) and the University of Marburg were the first to make stacked sandwich complexes form a nano-sized ring. Physical and other properties of these cyclocene structures will now be further investigated. The researchers report their findings in Nature.

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10141-cover2-cyclob_rdax_1024x683_98sNature / c&en
strontium cyclocene “standout molecule of 2023

Readers of Chemistry & Engineering News (C&EN) elected strontium cyclocene as “standout molecule of 2023“.

In their quest for determining this year’s “most curious, wondrous, and just plain neat molecules“ their choice fell on this new type of supersize sandwich complex created by the groups of F. Weigend, M. Kappes and P. Roesky within the framework of CRC 1573 by coaxing 18 metallocene units to curve into a nanometer-scale ring (a “cyclocene“, cf. Nature paper).

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